08
Mar
2021
BNMC
NY
United States of America

Dr. Edward Snell is a biophysicist who leads the Hauptman-Woodward Medical Research Institute. He has almost 80 publications, four book chapters, and two books. He and serves on numerous advisory committees. The Snell Group is engaged in methods development that leads to a deeper understanding of biological structure, function, and mechanism. The laboratory is predominantly interested in crystallography with an ever-increasing focus on complementary techniques to extend and enhance the understanding of dynamics on top of the structure. Ongoing projects include the enhancement of high-throughput crystallization processes, accurate interpretation of metalloprotein structure, and specific structural projects related to cancer therapy and treatment. Dr. Snell is also the Director of the NSF BioXFEL Science and Technology Center, an effort to develop the biological applications of X-ray Free Electron Lasers.

 

Dr. Sarah Bowman's interests include developing new methods for crystallization of biomolecules, new methods for detection of nanocrystals, and new methods for in situ X-ray data collection. My research lab is interested in developing new methods that combine crystallographic and spectroscopic approaches to answer fundamental questions about protein biochemistry, especially in proteins that contain metals. We are working to develop spectroscopic methods for single crystals (electron paramagnetic resonance, UV-visible microspectrophotometry, and energy dispersive X-ray spectroscopy for elemental analysis) to be used in parallel with crystallography.